Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404343 | 0.93 | MAOA (0.50) | L3MBTL1MEN1KMT2AMAPTAPP | |
| SCHEMBL3975481 | 0.90 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AMAPTAPP | |
| SCHEMBL9173175 | 0.82 | ALDH1A1 (0.55) | L3MBTL1MEN1KMT2AMAPTPDE4A | |
| SCHEMBL4602308 | 0.81 | MAPT (0.49) | L3MBTL1MEN1KMT2AMAPTAPP | |
| SCHEMBL92745 | 0.79 | KMT2A (0.50) | L3MBTL1MEN1KMT2AMAPTAPP | |
| SCHEMBL7835433 | 0.79 | PDE4A (0.49) | L3MBTL1MEN1KMT2AMAPTPDE4A | |
| SCHEMBL4603760 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2AMAPTAPP | |
| SCHEMBL790531 | 0.78 | MAPT (0.47) | L3MBTL1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL2261435 | 0.78 | MAOA (0.52) | L3MBTL1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL859288 | 0.78 | ALDH1A1 (0.54) | L3MBTL1MEN1KMT2AMAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503837-B | Substituted quinazoline analog derivative and its application with Aurora kinase inhibitory activity | 中山大学 | 2018-06-29 | — | — | CN | disclosed |