Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570666 | 0.85 | NPC1 (0.41) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL18589736 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL3204184 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2MAOAKDM4E | |
| SCHEMBL29690092 | 0.84 | CASP3 (0.48) | NPC1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL2010849 | 0.84 | CASP3 (0.48) | NPC1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL234460 | 0.83 | NPC1 (0.38) | MEN1KMT2ACDC25BNPC1MAPT | |
| SCHEMBL30307825 | 0.83 | NPC1 (0.38) | MEN1KMT2ACDC25BNPC1MAPT | |
| Charcoal, Activated SCHEMBL8610664 | 0.80 | NPC1 (0.36) | MEN1KMT2ACDC25BNPC1MAPT | |
| SCHEMBL18494509 | 0.78 | AHR (0.38) | MAPK1KDM4EALOX15TDP1TSHR | |
| SCHEMBL18619366 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250034-A | A kind of biphenyl compound and its application in 1,3,6- tribromo pyrenes are prepared | 李现伟 | 2018-07-06 | — | — | CN | disclosed |