Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28225483 | 0.87 | EIF4A3 (0.49) | ALOX15MEN1KMT2ARXFP1FLT3 | |
| Hydrochloric Acid SCHEMBL28226226 | 0.86 | EIF4A3 (0.48) | ALOX15MEN1KMT2ARXFP1FLT3 | |
| SCHEMBL28225523 | 0.86 | PLG (0.38) | ALOX15MEN1KMT2ARXFP1FLT3 | |
| SCHEMBL8985790 | 0.84 | XDH (0.47) | XDHALOX15MEN1KMT2ARXFP1 | |
| SCHEMBL28053874 | 0.75 | EGFR (0.62) | MEN1KMT2ALMNATP53L3MBTL1 | |
| SCHEMBL3275257 | 0.73 | FLT3 (0.59) | XDHALOX15MEN1KMT2AFLT3 | |
| SCHEMBL29919471 | 0.73 | FLT3 (0.59) | XDHALOX15MEN1KMT2AFLT3 | |
| SCHEMBL6421763 | 0.73 | KIF11 (0.53) | XDHALOX15FLT3PDGFRBPDGFRA | |
| SCHEMBL2815266 | 0.73 | FLT3 (0.56) | XDHALOX15FLT3PDGFRBPDGFRA | |
| SCHEMBL27688093 | 0.73 | TUBB4A (0.41) | MEN1KMT2AKDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-B | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2018-08-17 | — | — | CN | disclosed |