Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860936 | 0.91 | DYRK1A (0.59) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28227101 | 0.91 | DYRK1A (0.62) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28226349 | 0.91 | USP2 (0.54) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28226387 | 0.91 | CASP3 (0.56) | HTTLMNAMAPTKDM4ERECQL | |
| SCHEMBL28226338 | 0.91 | CASP3 (0.52) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28226336 | 0.91 | CASP3 (0.54) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28226361 | 0.88 | MAPT (0.49) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28227100 | 0.86 | KDM4E (0.56) | HTTLMNAMAPTKDM4ERECQL | |
| SCHEMBL28226308 | 0.85 | LRRK2 (0.60) | HTTLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28226392 | 0.85 | AKT1 (0.51) | HTTLMNASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |