Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860936 | 0.91 | DYRK1A (0.59) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28226338 | 0.91 | CASP3 (0.52) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28226336 | 0.91 | CASP3 (0.54) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28227094 | 0.91 | HTT (0.56) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28226349 | 0.89 | USP2 (0.54) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28226361 | 0.88 | MAPT (0.49) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28227101 | 0.85 | DYRK1A (0.62) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28860940 | 0.84 | HSD17B10 (0.56) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28226392 | 0.83 | AKT1 (0.51) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL28227100 | 0.82 | KDM4E (0.56) | CASP3SENP8SENP7SENP6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |