Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227094 | 0.91 | HTT (0.56) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28860936 | 0.90 | DYRK1A (0.59) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28226392 | 0.89 | AKT1 (0.51) | DYRK1AMAPTLMNAHTTKDM4E | |
| SCHEMBL28226349 | 0.85 | USP2 (0.54) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28226336 | 0.85 | CASP3 (0.54) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28226338 | 0.85 | CASP3 (0.52) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28226387 | 0.85 | CASP3 (0.56) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28227100 | 0.84 | KDM4E (0.56) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28226361 | 0.83 | MAPT (0.49) | DYRK1APIK3CAMTORMAPTLMNA | |
| SCHEMBL28860940 | 0.83 | HSD17B10 (0.56) | MAPTLMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |