Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA4 | P22748 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228051 | 0.88 | CHIT1 (0.50) | CA1CA2CA4CA9 | |
| SCHEMBL25154276 | 0.85 | CA1 (0.48) | CA1CA2CA4CA9RECQL | |
| SCHEMBL25154742 | 0.85 | CA1 (0.48) | CA1CA2CA4CA9RECQL | |
| SCHEMBL25154275 | 0.83 | RECQL (0.52) | RECQLSMN1; SMN2 | |
| SCHEMBL30259445 | 0.82 | SIGMAR1 (0.48) | CA1CA2CA4CA9RECQL | |
| SCHEMBL23539643 | 0.80 | RECQL (0.51) | RECQLSMN1; SMN2 | |
| SCHEMBL23556669 | 0.80 | RECQL (0.51) | RECQLSMN1; SMN2 | |
| SCHEMBL24337680 | 0.80 | RECQL (0.51) | RECQLSMN1; SMN2 | |
| SCHEMBL31598338 | 0.76 | — | — | |
| SCHEMBL30303092 | 0.76 | L3MBTL1 (0.48) | CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127488-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2003-11-12 | — | — | CN | disclosed |
| EP-0907643-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | disclosed |
| US-5919777-A | PIPERAZINE DERIVATIVES USEFUL FOR TREATING MEDICAL DISORDERS RESULTING FROM A GROWTH HORMONE DEFIENCY | NOVO NORDISK A/S (DK) | 1999-07-06 | — | — | US | disclosed |
| CN-1216537-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-05-12 | — | — | CN | disclosed |
| EP-0907643-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997040023-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |