Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318245 | 0.82 | LMNA (0.49) | SCN9AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL28531957 | 0.82 | FAAH (0.51) | SCN9AALDH1A1ALDH2ALDH3A1KDM4E | |
| SCHEMBL16264926 | 0.81 | ALDH1A1 (0.52) | SCN9AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL2489952 | 0.79 | OPRL1 (0.60) | SCN9ACES1CDC25AALDH1A1ALDH2 | |
| SCHEMBL7836181 | 0.78 | LMNA (0.44) | SCN9AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11715258 | 0.76 | CNR1 (0.54) | SCN9ACES1CDC25A | |
| SCHEMBL19467826 | 0.75 | MEN1 (0.51) | ALDH1A1ALDH2ALDH3A1MEN1GAA | |
| SCHEMBL29456280 | 0.75 | MEN1 (0.51) | ALDH1A1ALDH2ALDH3A1MEN1GAA | |
| SCHEMBL16264955 | 0.75 | OPRL1 (0.55) | SCN9AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL4167285 | 0.74 | ALDH1A1 (0.49) | SCN9AALDH1A1ALDH2ALDH3A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299137-B | Selective fluorination method of isatin hydrazone compound | 中南大学 | 2020-04-14 | — | — | CN | disclosed |
| CN-108299137-A | A kind of isatin hydrazone compounds selective fluorination method | 中南大学 | 2018-07-20 | — | — | CN | disclosed |