Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.34 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422607 | 0.76 | MEN1 (0.47) | TAS2R14ADRA1DADRA1AADRA1BKCNK18 | |
| SCHEMBL23978923 | 0.64 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BMAPK10MEN1 | |
| SCHEMBL9693871 | 0.64 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BMAPK10MEN1 | |
| SCHEMBL10599951 | 0.62 | KDM4E (0.45) | ADRA1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1232419 | 0.61 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL18856198 | 0.60 | PABPC1 (0.43) | ADRA1DADRA1AADRA1BMAPK10MEN1 | |
| SCHEMBL12853990 | 0.60 | PTPRC (0.44) | ADRA1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29850028 | 0.59 | KMT2A (0.49) | ADRA1DADRA1AADRA1BMAPK10MEN1 | |
| SCHEMBL18966077 | 0.59 | KMT2A (0.49) | ADRA1DADRA1AADRA1BMAPK10MEN1 | |
| SCHEMBL22618034 | 0.59 | RET (0.49) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191774-A | Heterocycle compound, preparation method and use | 中国药科大学 | 2018-06-22 | — | — | CN | claimed |
| CN-108191774-A | Heterocycle compound, preparation method and use | 中国药科大学 | 2018-06-22 | — | — | CN | disclosed |