Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28484148 | 0.81 | IMPDH2 (0.43) | IMPDH2TSHRKDM4EVCPALDH1A1 | |
| SCHEMBL28229271 | 0.76 | CYP1A2 (0.42) | KDM4EALDH1A1CA1CA2MEN1 | |
| SCHEMBL31487098 | 0.70 | GAA (0.47) | KDM4EALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28229272 | 0.69 | CYP1A2 (0.35) | IMPDH2TSHRKDM4EALDH1A1AR | |
| SCHEMBL1429109 | 0.66 | HPGD (0.54) | IMPDH2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL506644 | 0.66 | IMPDH2 (0.59) | IMPDH2TSHRKDM4ENR3C1NR3C2 | |
| SCHEMBL3220763 | 0.66 | IMPDH2 (0.42) | IMPDH2TSHRKDM4EPGRNR3C1 | |
| SCHEMBL28164512 | 0.66 | NOTUM (0.39) | IMPDH2TSHRKDM4ENOTUMALDH1A1 | |
| SCHEMBL45954 | 0.65 | CA1 (0.54) | IMPDH2TSHRKDM4EALDH1A1AR | |
| SCHEMBL29489124 | 0.65 | CA1 (0.54) | IMPDH2TSHRKDM4EALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349949-A | N- substituted indole derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2018-07-31 | — | — | CN | disclosed |