SCHEMBL45954

SCHEMBL45954

N#Cc1cccc2c(C#N)cccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
IMPDH2 P12268 3/20 0.52
IMPDH1 P20839 2/20 0.52
PNMT P11086 1/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
TSHR P16473 1/20 0.48
AR P10275 1/20 0.47
DYRK1A Q13627 3/20 0.45
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
MCL1 Q07820 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
MEN1 O00255 1/20 0.40
CACNA1B Q00975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489124 1.00 CA1 (0.54) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL9746966 0.94 PNMT (0.52) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL11228244 0.94 IMPDH2 (0.59) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL151936 0.88 IMPDH2 (0.64) CA1CA2IMPDH2IMPDH1KDM4E
SCHEMBL29489135 0.88 IMPDH2 (0.64) CA1CA2IMPDH2IMPDH1KDM4E
SCHEMBL1343833 0.85 DYRK1A (0.53) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL9694692 0.85 CA1 (0.44) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL2988058 0.85 IDO1 (0.46) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL31588265 0.85 ALDH1A1 (0.59) CA1CA2IMPDH2IMPDH1PNMT
SCHEMBL1343967 0.85 CYP1A2 (0.59) CA1CA2IMPDH2IMPDH1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016205405-A1 COORDINATION POLYMER NDSU RESEARCH FOUNDATION (US) 2016-12-22 WO claimed
EP-2382241-B1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORP (JP) 2016-11-23 EP claimed
US-8785566-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2014-07-22 US claimed
JP-8113641-A None JP disclosed
CN-118251445-A Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same 信越化学工业株式会社 2024-06-25 CN disclosed
CN-112236464-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2024-02-23 CN disclosed
CN-117279780-A Laminated substrate, laminated body manufacturing method, laminated body with member for electronic device, and electronic device manufacturing method AGC株式会社 2023-12-22 CN disclosed
CN-112204076-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-113646393-B Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2023-09-19 CN disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-4040969-A ELECTROSTATOGRAPHIC DEVELOPER OF TONER ON FERROMAGNETIC CARRIER ON XEROX CORPORATION (US) 1977-08-09 US disclosed
US-4035310-A STYRENE-VINYL, STYRENE-ACRYLATE COPOLYMERS XEROX CORPORATION (US) 1977-07-12 US disclosed
US-4019842-A Apparatus for forming magnetite electrostatographic carriers XEROX CORPORATION (US) 1977-04-26 US disclosed
US-3969251-A ELECTROGRAPHY XEROX CORPORATION (US) 1976-07-13 US disclosed
US-3965160-A OXIDATION SUN VENTURES, INC. (US) 1976-06-22 US disclosed
US-3963486-A Electrophotographic imaging process employing epoxy-ester containing liquid developer RANK XEROX LTD. (EN) 1976-06-15 US disclosed
US-3947371-A Developer material with poly(p-xylylene) coated carrier XEROX CORPORATION (US) 1976-03-30 US disclosed
US-3945823-A Electrostatographic reversal development with developer comprising poly(p-xylene)-coated carrier particles XEROX CORPORATION (US) 1976-03-23 US disclosed
US-3942979-A ELECTROGRAPHY XEROX CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 CA1 3875/4885CA2 4554/4885IMPDH2 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.