Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245909 | 0.86 | NR4A2 (0.67) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL27859181 | 0.84 | NR4A2 (0.52) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL14159256 | 0.83 | NR4A2 (0.71) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL27707844 | 0.83 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL13564517 | 0.82 | NR4A2 (0.69) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL30373303 | 0.82 | NR4A2 (0.69) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2429622 | 0.82 | NR4A2 (0.69) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28215959 | 0.82 | L3MBTL1 (0.66) | ALDH1A1LMNASMN1; SMN2KMT2AL3MBTL1 | |
| Dimethylamine SCHEMBL7778089 | 0.81 | NR4A2 (0.68) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL30117222 | 0.81 | LMNA (0.74) | NR4A2ALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467391-A | 3-（1,3- benzodiazole -2- difluoromethyls）3-hydroxyindole quinoline ketone compounds and preparation method thereof | 上海大学 | 2018-08-31 | — | — | CN | disclosed |