Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365156 | 0.89 | TAAR1 (0.54) | TAAR1GPR52ANPEPDHODHTSHR | |
| SCHEMBL5281640 | 0.78 | TAAR1 (0.50) | TAAR1GPR52ANPEPTSHRHPGD | |
| SCHEMBL16995424 | 0.76 | TSHR (0.50) | TAAR1GPR52ANPEPTSHRHPGD | |
| SCHEMBL15532115 | 0.75 | TAAR1 (0.47) | TAAR1GPR52ANPEPTSHRHPGD | |
| SCHEMBL31517195 | 0.74 | SLC6A2 (0.48) | TAAR1DHODHTSHRSLC6A2SLC6A4 | |
| SCHEMBL7630645 | 0.74 | SLC6A2 (0.48) | TAAR1DHODHTSHRSLC6A2SLC6A4 | |
| SCHEMBL30521500 | 0.74 | SLC6A2 (0.61) | TAAR1GPR52TSHRIDO1SLC6A2 | |
| SCHEMBL623814 | 0.74 | SLC6A2 (0.61) | TAAR1GPR52TSHRIDO1SLC6A2 | |
| SCHEMBL15026138 | 0.74 | TAAR1 (0.50) | TAAR1GPR52ANPEPTSHRHPGD | |
| SCHEMBL16393648 | 0.73 | GPR52 (0.49) | TAAR1GPR52TSHRHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349949-A | N- substituted indole derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2018-07-31 | — | — | CN | disclosed |