Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887450 | 0.90 | FGFR1 (0.38) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL29141665 | 0.83 | ADORA2A (0.41) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL27854932 | 0.81 | LMNA (0.45) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL3157542 | 0.80 | HSD17B10 (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4194087 | 0.80 | LMNA (0.41) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL28704048 | 0.80 | TK1 (0.43) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL5839419 | 0.79 | FGFR1 (0.40) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL29601304 | 0.75 | FGFR1 (0.41) | FGFR1FGFR4KDM4EALDH1A1HDAC6 | |
| SCHEMBL30586403 | 0.75 | FGFR1 (0.46) | FGFR1FGFR4KDM4EALDH1A1HPGD | |
| SCHEMBL27773226 | 0.75 | POLB (0.44) | FGFR1FGFR4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314685-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-108484605-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-108314685-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-07-24 | — | — | CN | disclosed |