Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491787 | 0.75 | CYP19A1 (0.68) | DAOCYP19A1FGFR1CALM1AKR1B1 | |
| SCHEMBL23409093 | 0.73 | FGFR2 (0.52) | DAOCYP19A1FGFR1FGFR2FGFR3 | |
| SCHEMBL27953115 | 0.72 | SCN4A (0.51) | LMNANPC1RAB9ASCN4A | |
| SCHEMBL1922681 | 0.72 | CYP19A1 (0.51) | DAOCYP19A1FGFR1FGFR2FGFR3 | |
| SCHEMBL28861830 | 0.71 | DAO (0.50) | DAOCYP19A1FGFR1FGFR2FGFR3 | |
| SCHEMBL20227222 | 0.71 | FGFR2 (0.50) | DAOCYP19A1FGFR1FGFR2FGFR3 | |
| SCHEMBL1149871 | 0.71 | USP2 (0.55) | DAOUSP2LMNAHRH2SCN4A | |
| SCHEMBL26793344 | 0.71 | — | — | |
| SCHEMBL28891744 | 0.70 | CALM1 (0.75) | CYP19A1CALM1AKR1B1 | |
| SCHEMBL18053017 | 0.70 | FGFR2 (0.49) | DAOCYP19A1FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530361-A | A kind of synthesis technology of 5- [2- (3,5- Dimethoxyphenyls) ethyl] -1H- pyrazoles -3- amine | 重庆医药高等专科学校 | 2018-09-14 | — | — | CN | claimed |
| CN-108530361-A | A kind of synthesis technology of 5- [2- (3,5- Dimethoxyphenyls) ethyl] -1H- pyrazoles -3- amine | 重庆医药高等专科学校 | 2018-09-14 | — | — | CN | disclosed |
| CN-108530361-A | A kind of synthesis technology of 5- [2- (3,5- Dimethoxyphenyls) ethyl] -1H- pyrazoles -3- amine | 重庆医药高等专科学校 | 2018-09-14 | — | — | CN | disclosed |