Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 12/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | IGF1R | P08069 | 3/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922681 | 0.82 | CYP19A1 (0.51) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL20227222 | 0.81 | FGFR2 (0.50) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL18053017 | 0.80 | FGFR2 (0.49) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL16070500 | 0.77 | HCAR2 (0.62) | FGFR2FGFR1FGFR3DAOFGFR4 | |
| SCHEMBL16070556 | 0.76 | THRB (0.45) | FGFR2FGFR1FGFR3DAOFGFR4 | |
| SCHEMBL9491787 | 0.75 | CYP19A1 (0.68) | FGFR1DAOKDRCYP19A1AKR1B1 | |
| SCHEMBL25068996 | 0.75 | FGFR2 (0.46) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL28233100 | 0.73 | DAO (0.49) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL3935675 | 0.73 | FGFR2 (0.44) | FGFR2FGFR1FGFR3DAOKDR | |
| SCHEMBL20224131 | 0.72 | DAO (0.52) | FGFR2FGFR1FGFR3DAOKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |