Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537360 | 0.74 | HTT (0.39) | HTTRAB9ANTSR1NPSR1KDM4E | |
| SCHEMBL13327127 | 0.73 | MAPT (0.38) | HTTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2825657 | 0.72 | ALDH1A1 (0.47) | HTTRAB9AKDM4ELMNATDP1 | |
| SCHEMBL2826280 | 0.72 | MGLL (0.30) | MGLL | |
| SCHEMBL18840159 | 0.71 | HTT (0.36) | HTTRAB9ANTSR1NPSR1KDM4E | |
| SCHEMBL18843394 | 0.71 | HTT (0.36) | HTTRAB9ANTSR1NPSR1KDM4E | |
| SCHEMBL7806229 | 0.70 | HTT (0.43) | HTTRAB9AKDM4ELMNATDP1 | |
| SCHEMBL2828765 | 0.70 | — | — | |
| SCHEMBL10233911 | 0.69 | HTT (0.36) | HTTRAB9ANTSR1NPSR1KDM4E | |
| SCHEMBL18840210 | 0.69 | ALDH1A1 (0.46) | HTTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101056893-B | N-substituted imides as polymerization initiators | CIBA SC HOLDING AG | 2011-06-08 | — | — | CN | disclosed |
| EP-1828258-B1 | N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS | BASF SE (DE) | 2010-06-30 | — | — | EP | disclosed |
| EP-1828258-B1 | N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS | BASF SE (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723399-B2 | N-substituted imides as polymerization initiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-05 | — | — | US | disclosed |
| CN-101056893-A | N-substituted imides as polymerization initiators | CIBA SC HOLDING AG (CH) | 2007-10-17 | — | — | CN | disclosed |
| EP-1828258-A1 | N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006051047-A1 | N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132600-A1 | N-Substituted Imides As Polymerization Initiators | NR1H3, SIGMAR1, NR1H2 | HTT 1883/4885PDE4A 4716/4885PDE4B 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.