Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823406 | 0.88 | PPARD (0.43) | PPARDEGLN1EGLN3ACACB | |
| SCHEMBL2068042 | 0.79 | PPARD (0.53) | PPARD | |
| SCHEMBL2827433 | 0.77 | PPARG (0.38) | PPARDEGLN1EGLN3ACACB | |
| SCHEMBL2822346 | 0.73 | PPARD (0.41) | PPARD | |
| SCHEMBL2827431 | 0.70 | PPARG (0.40) | PPARDEGLN1EGLN3ACACB | |
| SCHEMBL2069047 | 0.63 | PPARD (0.59) | PPARD | |
| SCHEMBL2822197 | 0.62 | GRM5 (0.43) | PPARD | |
| SCHEMBL16624600 | 0.61 | TSHR (0.48) | EGLN1 | |
| SCHEMBL5176957 | 0.61 | ACACB (0.40) | ACACB | |
| SCHEMBL1692261 | 0.59 | APP (0.54) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |