Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822348 | 0.86 | PPARD (0.41) | PPARDGRM5CYP2C9HPGDCYP2C19 | |
| SCHEMBL2823406 | 0.85 | PPARD (0.43) | PPARD | |
| SCHEMBL2822191 | 0.77 | GRM5 (0.43) | PPARDGRM5LMNAHPGD | |
| SCHEMBL2822197 | 0.66 | GRM5 (0.43) | PPARDGRM5CYP2C9HPGDCYP2C19 | |
| SCHEMBL2821756 | 0.62 | GRM5 (0.41) | GRM5 | |
| SCHEMBL2822183 | 0.57 | PPARD (0.44) | PPARDGRM5HPGD | |
| SCHEMBL719360 | 0.57 | LMNA (0.57) | GRM5LMNACYP1A2 | |
| SCHEMBL20015814 | 0.57 | LMNA (0.57) | GRM5LMNACYP1A2 | |
| Charcoal, Activated SCHEMBL31286310 | 0.55 | KCNH2 (0.54) | GRM5LMNACYP1A2 | |
| SCHEMBL12538577 | 0.55 | GRM5 (0.59) | GRM5LMNACYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |