Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | RORA | P35398 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280844 | 1.00 | RORC (0.50) | RORCRORAGAAPSIP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28691545 | 0.98 | GAA (0.52) | RORCRORAGAAPSIP1HSD17B10 | |
| SCHEMBL21936325 | 0.81 | RORC (0.47) | RORCRORAGAAPSIP1KMT2A | |
| SCHEMBL29070035 | 0.81 | RORC (0.47) | RORCRORAGAAPSIP1KMT2A | |
| Carbamic Acid SCHEMBL23632118 | 0.81 | GAA (0.47) | RORCRORAGAAPSIP1ALDH1A1 | |
| Carbamic Acid SCHEMBL23632117 | 0.81 | GAA (0.47) | RORCRORAGAAPSIP1ALDH1A1 | |
| SCHEMBL166813 | 0.80 | PTGS2 (0.53) | GAAPSIP1CYP2C9 | |
| SCHEMBL11516910 | 0.79 | CA2 (0.53) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL21570439 | 0.79 | GAA (0.46) | RORCRORAGAAPSIP1TDP1 | |
| SCHEMBL21570441 | 0.79 | GAA (0.46) | RORCRORAGAAPSIP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-108463458-A | MODULATORS OF ROR-GAMMA | 生命医药公司 | 2018-08-28 | — | — | CN | disclosed |