Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233679 | 0.79 | MAPT (0.56) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL28233776 | 0.73 | TLR8 (0.45) | TLR8LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28614010 | 0.71 | MAPT (0.51) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL27667670 | 0.71 | TSHR (0.47) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL4421242 | 0.70 | CHEK1 (0.44) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL27647109 | 0.70 | TLR8 (0.55) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL27667678 | 0.70 | TLR8 (0.55) | TLR8MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9123032 | 0.69 | CA1 (0.51) | TLR8MAPTMEN1KMT2ALMNA | |
| SCHEMBL2338357 | 0.68 | POLB (0.49) | KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL28233689 | 0.68 | LMNA (0.57) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-A | Microtubule inhibitors and its preparation method and application | 四川大学 | 2018-08-17 | — | — | CN | disclosed |