Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233679 | 0.81 | MAPT (0.56) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL4494474 | 0.77 | ALDH1A1 (0.52) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL28624707 | 0.75 | RIPK2 (0.46) | MAPTMEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL9123032 | 0.72 | CA1 (0.51) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL8310316 | 0.72 | ADORA2A (0.51) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL4714412 | 0.72 | SMN1; SMN2 (0.54) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL8355956 | 0.72 | RIPK2 (0.71) | SRCKDRRIPK2 | |
| SCHEMBL28624694 | 0.72 | SRC (0.48) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL28234723 | 0.71 | TLR8 (0.55) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28233689 | 0.71 | LMNA (0.57) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-B | Microtubule inhibitors, methods of preparation and uses thereof | 成都威斯克生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |