Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614010 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28234723 | 0.79 | TLR8 (0.55) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL2763737 | 0.79 | TLR8 (0.45) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL1915201 | 0.79 | MEN1 (0.51) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL2764180 | 0.78 | TLR8 (0.44) | MAPTMEN1KMT2ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL9123032 | 0.77 | CA1 (0.51) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28233689 | 0.76 | LMNA (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28233778 | 0.75 | MEN1 (0.62) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL28234764 | 0.74 | PIK3CD (0.42) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL2765451 | 0.74 | HSD17B10 (0.49) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-B | Microtubule inhibitors, methods of preparation and uses thereof | 成都威斯克生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-108409663-A | Microtubule inhibitors and its preparation method and application | 四川大学 | 2018-08-17 | — | — | CN | disclosed |