SCHEMBL28235083

SCHEMBL28235083

C=C(C(=O)ON)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899520 0.76 ALDH1A1 (0.50) ALDH1A1
SCHEMBL2078326 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL26103001 0.74 DGAT1 (0.36) ALDH1A1
SCHEMBL2186415 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29117402 0.73 TSHR (0.30)
SCHEMBL4144641 0.72 HSD17B10 (0.48) ALDH1A1
SCHEMBL8563426 0.72 SLC7A5 (0.31)
SCHEMBL534164 0.70 THRB (0.34) ALDH1A1
SCHEMBL9747666 0.70 TSHR (0.40)
SCHEMBL4730018 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108503637-A A kind of novel N asymmetric acid imide molecules and its organic-inorganic composite body 桂林理工大学 2018-09-07 CN claimed
CN-108424405-A The total prodrug and the preparation method and application thereof of Vorinostat and taxol 华东师范大学 2018-08-21 CN claimed
CN-108503637-A A kind of novel N asymmetric acid imide molecules and its organic-inorganic composite body 桂林理工大学 2018-09-07 CN disclosed
CN-108424405-A The total prodrug and the preparation method and application thereof of Vorinostat and taxol 华东师范大学 2018-08-21 CN disclosed