Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025248 | 0.94 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11149035 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL28036579 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL6283990 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL28094096 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL4597172 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL10678903 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL3023996 | 0.78 | CES1 (0.61) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL3024396 | 0.78 | CDC25A (0.61) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL6283905 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430994-A | Compound, composition and method for adjusting CFTR | 蛋白质平衡治疗股份有限公司 | 2018-08-21 | — | — | CN | disclosed |