Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | BID | P55957 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL14331163 | 1.00 | PPARA (0.52) | PPARABIDMCL1BCL2L1BAK1 | |
| Phosphoric Acid SCHEMBL28536238 | 0.94 | LIPG (0.47) | PPARABIDMCL1BCL2L1BAK1 | |
| Phosphoric Acid SCHEMBL28166823 | 0.94 | PPARA (0.48) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27513992 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27594350 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1839396 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27543186 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1838555 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1835039 | 0.90 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL8521601 | 0.90 | LIPG (0.55) | PPARABIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473649-A | High modulus thermoplastic polyurethane | 路博润先进材料公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108368226-A | CRYSTALLINE HIGH MODULUS THERMOPLASTIC POLYURETHANE | 路博润先进材料公司 | 2018-08-03 | — | — | CN | disclosed |