Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28235490 | 0.94 | PPARA (0.52) | PPARACETPSOAT1BIDMCL1 | |
| Phosphoric Acid SCHEMBL14331163 | 0.94 | PPARA (0.52) | PPARACETPSOAT1BIDMCL1 | |
| Bicarbonate SCHEMBL1839405 | 0.90 | PPARA (0.53) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| Phosphoric Acid SCHEMBL14829855 | 0.90 | PPARA (0.50) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| SCHEMBL367335 | 0.89 | DPP4 (0.52) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| SCHEMBL27835204 | 0.88 | PPARA (0.48) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| Phosphoric Acid SCHEMBL28536238 | 0.88 | LIPG (0.47) | PPARACETPSOAT1BIDMCL1 | |
| Ethane SCHEMBL1275986 | 0.88 | DPP4 (0.50) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| SCHEMBL28825457 | 0.88 | DPP4 (0.50) | PPARAKMT2ADPP4FOLH1PTGER1 | |
| SCHEMBL27424929 | 0.88 | DPP4 (0.50) | PPARAKMT2ADPP4FOLH1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098994-B | Three-dimensional contouring material, three-dimensional contouring combination of materials, the manufacturing method and its manufacturing device of three-dimensional contouring object | 株式会社理光 | 2019-07-19 | — | — | CN | disclosed |
| CN-108473649-A | High modulus thermoplastic polyurethane | 路博润先进材料公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108368226-A | CRYSTALLINE HIGH MODULUS THERMOPLASTIC POLYURETHANE | 路博润先进材料公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-107098994-A | Three-dimensional contouring material, three-dimensional contouring combination of materials, the manufacture method and its manufacture device of three-dimensional contouring thing | 株式会社理光 | 2017-08-29 | — | — | CN | disclosed |