Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634461 | 0.82 | PTPN1 (0.70) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL13265852 | 0.80 | MEN1 (0.65) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL13265853 | 0.78 | MEN1 (0.63) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL10665983 | 0.76 | KMT2A (0.62) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL617744 | 0.76 | ALDH1A1 (0.72) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL4284641 | 0.75 | PKM (0.72) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL4287167 | 0.75 | L3MBTL1 (0.66) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL30873118 | 0.74 | MEN1 (0.58) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL27183381 | 0.74 | MEN1 (0.58) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL19771115 | 0.74 | ALDH1A1 (0.74) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358869-B | A kind of N- benzothiazolyl benzsulfamide analog derivative, Preparation method and use | 河北师范大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108358869-A | A kind of N- benzothiazolyls benzsulfamide analog derivative, Preparation method and use | 河北师范大学 | 2018-08-03 | — | — | CN | disclosed |