Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17234580 | 0.83 | PRMT1 (0.47) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL466337 | 0.83 | PRMT1 (0.47) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL19933297 | 0.82 | ADRA1A (0.47) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL25366603 | 0.80 | PRMT1 (0.44) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL2035521 | 0.78 | PRMT1 (0.54) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL585705 | 0.78 | PRMT1 (0.55) | PRMT1ADRA1ALMNAEPHX2TSHR | |
| SCHEMBL8944734 | 0.76 | PRMT1 (0.59) | PRMT1ADRA1APLA2G4ALMNAEPHX2 | |
| SCHEMBL33717 | 0.74 | PRMT1 (0.50) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL31372702 | 0.74 | PRMT1 (0.50) | PRMT1ADRA1AATMPLA2G4ALMNA | |
| SCHEMBL3280998 | 0.74 | PRMT1 (0.50) | PRMT1ADRA1AATMPLA2G4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108367043-A | The conjugate of quaternized tubulysin compound | 西雅图基因公司 | 2018-08-03 | — | — | CN | disclosed |