Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 19/20 | 0.43 |
| ▸ | HSD11B2 | P80365 | 13/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823384 | 0.83 | HSD11B1 (0.47) | P2RX7HSD11B1HSD11B2 | |
| SCHEMBL2826092 | 0.82 | PPARA (0.40) | HSD11B1HSD11B2 | |
| SCHEMBL2827329 | 0.81 | PPARA (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL2834257 | 0.81 | HSD11B1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL2824588 | 0.80 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL2823709 | 0.79 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL2828382 | 0.79 | HSD11B1 (0.37) | HSD11B1HSD11B2 | |
| SCHEMBL2823635 | 0.78 | HSD11B1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL2823628 | 0.78 | HSD11B1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL2824811 | 0.78 | HSD11B1 (0.43) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |