Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | HSD11B2 | P80365 | 5/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826228 | 0.90 | SIGMAR1 (0.41) | HSD11B1HSD11B2P2RX7SIGMAR1 | |
| SCHEMBL2823673 | 0.83 | HSD11B1 (0.44) | HSD11B1HSD11B2P2RX7USP30GPR6 | |
| SCHEMBL2823633 | 0.83 | P2RX7 (0.44) | HSD11B1HSD11B2P2RX7 | |
| SCHEMBL2827937 | 0.82 | HSD11B1 (0.47) | HSD11B1HSD11B2P2RX7USP30 | |
| SCHEMBL2827946 | 0.81 | HSD11B1 (0.46) | HSD11B1HSD11B2USP30 | |
| SCHEMBL2823388 | 0.81 | HSD11B1 (0.49) | HSD11B1HSD11B2USP30 | |
| SCHEMBL2823380 | 0.81 | HSD11B1 (0.49) | HSD11B1HSD11B2USP30 | |
| SCHEMBL2824155 | 0.81 | HSD11B1 (0.47) | HSD11B1HSD11B2USP30GPR6 | |
| SCHEMBL2824153 | 0.81 | HSD11B1 (0.47) | HSD11B1HSD11B2USP30GPR6 | |
| SCHEMBL2824621 | 0.79 | HSD11B1 (0.43) | HSD11B1HSD11B2P2RX7SIGMAR1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |