Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997818 | 0.90 | ACHE (0.60) | HPGDACHEL3MBTL3L3MBTL1KDM4E | |
| SCHEMBL28200535 | 0.82 | HPGD (0.61) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL3314769 | 0.81 | HPGD (0.59) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL6198935 | 0.81 | RECQL (0.75) | HPGDALDH1A1ACHELMNAHIF1A | |
| SCHEMBL7232912 | 0.81 | ALDH1A1 (0.64) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL16442058 | 0.81 | ALDH1A1 (0.64) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL18166095 | 0.81 | RECQL (0.75) | HPGDALDH1A1ACHELMNAHIF1A | |
| SCHEMBL1520334 | 0.81 | ALDH1A1 (0.64) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL27970474 | 0.81 | HPGD (0.59) | HPGDALDH1A1ACHEUSP2L3MBTL3 | |
| SCHEMBL6198934 | 0.81 | RECQL (0.75) | HPGDALDH1A1ACHELMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108456208-A | Aza toroid compound and its preparation method and application | 广州市恒诺康医药科技有限公司 | 2018-08-28 | — | — | CN | disclosed |