Crotonic Acid

Crotonic Acid

SCHEMBL28236702

CC=CC(=O)O.CCCCC(C(N)=O)(C(C)C)C(C)C

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.34
BACE1 P56817 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33
EPHX1 P07099 1/20 0.33
PTPN1 P18031 1/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32
GABRE P78334 2/20 0.32
GABRA6 Q16445 2/20 0.32
GABRG1 Q8N1C3 2/20 0.32
GABRG3 Q99928 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301700 0.85 CA1 (0.38) EPHX1MEN1FAAHTP53CYP1A2
SCHEMBL11398423 0.78 EPHX1 (0.43) EPHX1MEN1FAAHTP53CYP1A2
SCHEMBL25288074 0.73 LMNA (0.38) EPHX1CYP3A4
SCHEMBL22130341 0.70 SOAT1 (0.35) MEN1FAAHTP53CYP1A2CYP3A4
Crotonic Acid SCHEMBL11668490 0.69 L3MBTL1 (0.32) HCAR2
SCHEMBL27536667 0.68
SCHEMBL28131064 0.67 FAAH (0.41) MEN1FAAHTP53CYP1A2CYP3A4
Crotonic Acid SCHEMBL11681776 0.67
Valeric Acid SCHEMBL28091257 0.66 AKR1B1 (0.56) PTPN1MEN1CYP1A2CYP2C19KMT2A
Crotonic Acid SCHEMBL27718105 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473528-A High intensity sweetner 赛诺米克斯公司 2018-08-31 CN disclosed