Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.56 |
| ▸ | LPL | P06858 | 10/20 | 0.56 |
| ▸ | F11 | P03951 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181906 | 0.89 | LPL (0.60) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL1640431 | 0.87 | LIPG (0.43) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL20540359 | 0.82 | CA1 (0.43) | LIPGLPLF11CA1CA2 | |
| SCHEMBL20841744 | 0.81 | CA1 (0.43) | LIPGLPLF11CA1CA2 | |
| SCHEMBL20841728 | 0.81 | CA1 (0.43) | LIPGLPLF11CA1CA2 | |
| SCHEMBL25619880 | 0.80 | SNCA (0.38) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL15905496 | 0.80 | CA1 (0.42) | LIPGLPLF11CA1CA2 | |
| SCHEMBL20841763 | 0.80 | LPL (0.42) | LIPGLPLF11CA1CA2 | |
| SCHEMBL21092937 | 0.79 | LPL (0.40) | LIPGLPLF11ESR2 | |
| SCHEMBL3321210 | 0.79 | LIPG (0.67) | LIPGLPLF11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641507-B | Crosslinking agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-107641509-B | Crosslinking agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-10-20 | — | — | CN | disclosed |
| WO-2010069504-A1 | (3-OXO)PYRIDIN-4-YLUREA DERIVATIVES AS PDE4 INHIBITORS | ALMIRALL, S.A. (ES) | 2010-06-24 | — | — | WO | disclosed |
| EP-2196465-A1 | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |
| WO-2007049224-A1 | NOVEL HEXAHYDRO- OR OCTAHYDRO-CYCLOPENTA[C]PYRROLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-05-03 | — | — | WO | disclosed |