Levacetylleucine

Levacetylleucine

SCHEMBL282372

CC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
MEN1 O00255 1/20 0.64
LMNA P02545 1/20 0.64
KMT2A Q03164 1/20 0.64
MAPT P10636 2/20 0.60
KDM4E B2RXH2 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59
PTGS2 P35354 1/20 0.59
THPO P40225 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
FOLH1 Q04609 9/20 0.56
LAP3 P28838 3/20 0.53
NAALAD2 Q9Y3Q0 2/20 0.52
PLA2G2A P14555 2/20 0.50
PLA2G5 P39877 2/20 0.50
GRN P28799 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levacetylleucine SCHEMBL9438432 1.00 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL714003 1.00 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2AMAPT
Acetylleucine SCHEMBL282371 1.00 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL5527234 0.98 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL18954336 0.98 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL7923132 0.98 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL5532016 0.98 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2AMAPT
Acetylleucine SCHEMBL25408262 0.94 ALDH1A1 (0.88) ALDH1A1MEN1LMNAKMT2AMAPT
Levacetylleucine SCHEMBL6863674 0.92 ALDH1A1 (0.85) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL17948650 0.92 ALDH1A1 (0.85) ALDH1A1MEN1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4186 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122055147-A N-acetylleucine for the treatment of prodromal alpha-synucleinopathies 内在生物技术股份有限公司 2026-05-15 CN claimed
US-20260097008-A1 ACETYL LEUCINE FOR USE IN TREATING NIEMANN-PICK DISEASE TYPE C INTRABIO INC. 2026-04-09 US claimed
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US claimed
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH UNIV CALIFORNIA (US) 2026-03-19 US claimed
US-20260027077-A1 PHARMACEUTICAL COMPOSITIONS AND USES DIRECTED TO LYSOSOMAL STORAGE DISORDERS INTRABIO LTD (US) 2026-01-29 US claimed
US-12503719-B2 Metabolomic characterization of microorganisms LEWIS IAN ANDREW (CA) 2025-12-23 US claimed
US-20250353832-A1 PROCESS FOR THE PREPARATION OF AMINOPYRIDAZINE DERIVATIVES ADAMA MAKHTESHIM LTD. (IL) 2025-11-20 US claimed
EP-4650003-A2 COMBINATION THERAPY WITH ACETYL-LEUCINE AND MIGLUSTAT FOR TREATING A LYSOSOMAL STORAGE DISEASE IntraBio Ltd (GB) 2025-11-19 EP claimed
US-12458614-B2 Therapeutic agents for improved mobility and cognitive function and for treating neurodegenerative diseases and lysosomal storage disorders INTRABIO LTD (GB) 2025-11-04 US claimed
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 US claimed
US-5206162-A Process for making D-aminoacylase NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) 1993-04-27 US claimed
US-5194383-A Culturing alcaligenes denitrificans, separation, purification NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) 1993-03-16 US claimed
US-5134073-A Culture product of zoogloea ramigera DEGUSSA AKTIENGESELLSCHAFT (DE) 1992-07-28 US claimed
EP-0452000-A2 Preparation of optically active norbornyl amine derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1991-10-16 EP claimed
EP-0381997-A1 Microbially prepared N-acetyl-2,3-didehydroleucine acylase, process for its preparation and its use Degussa Aktiengesellschaft (DE) 1990-08-16 EP claimed
EP-0126886-B1 PROCESS FOR THE SEPARATION OF L-LEUCINE AND L-ISOLEUCINE Degussa Aktiengesellschaft (DE) 1986-06-11 EP claimed
EP-0126887-B1 PROCESS FOR OBTAINING PURE L-LEUCINE Degussa Aktiengesellschaft (DE) 1986-06-04 EP claimed
US-4562153-A Process for the separation of L-leucine and L-isoleucine DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-12-31 US claimed
US-4401827-A CARDIOTONIC AND ANTILIPEMIC AGENTS; BLOOD DISORDERS SIGMA-TAU (IT) 1983-08-30 US claimed