Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.56 |
| ▸ | LAP3 | P28838 | 3/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.50 |
| ▸ | GRN | P28799 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levacetylleucine SCHEMBL714003 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Acetylleucine SCHEMBL282371 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL282372 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL5532016 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL5527234 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL7923132 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Levacetylleucine SCHEMBL18954336 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| Acetylleucine SCHEMBL25408262 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL5551897 | 0.92 | ALDH1A1 (0.85) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL17948650 | 0.92 | ALDH1A1 (0.85) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358705-A | For reducing or preventing dental plaque or oral diseases, dentifrices, mouthwashes | THE PROCTER & GAMBLE COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5286480-A | Reducing dental plaque coating on teeth | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-15 | — | — | US | disclosed |