SCHEMBL28237442

SCHEMBL28237442

NCc1cccc(-c2ccnc(-c3cccc(CN)c3)n2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KARS1 Q15046 2/20 0.54
ADRB2 P07550 1/20 0.49
CDK8 P49336 1/20 0.48
LOXL2 Q9Y4K0 4/20 0.46
SYK P43405 1/20 0.44
ATR Q13535 1/20 0.44
CHEK1 O14757 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CFD P00746 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LOX P28300 1/20 0.41
LOXL3 P58215 1/20 0.41
NOS3 P29474 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28115954 0.85 HSP90AA1 (0.59) KARS1CDK8LOXL2SYKCHEK1
SCHEMBL112429 0.84 ADRB2 (0.68) KARS1ADRB2CDK8LOXL2SYK
SCHEMBL29676764 0.84 ADRB2 (0.68) KARS1ADRB2CDK8LOXL2SYK
SCHEMBL28135248 0.80 ADRB2 (0.62) ADRB2LOXL2MEN1KMT2AKDM4E
SCHEMBL28135257 0.80 ADRB2 (0.62) ADRB2LOXL2MEN1KMT2AKDM4E
SCHEMBL27807846 0.80 MEN1 (0.40) KARS1MEN1KMT2AKDM4EMAPT
SCHEMBL3649135 0.78 ADRB2 (0.56) ADRB2MEN1KMT2AKDM4EMAPT
SCHEMBL29793738 0.76 HRH3 (0.56) KARS1ADRB2CDK8LOXL2KDM4E
SCHEMBL2696099 0.76 HRH3 (0.56) KARS1ADRB2CDK8LOXL2KDM4E
SCHEMBL31667858 0.75 KARS1 (0.64) KARS1CDK8LOXL2SYKCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110402387-A The analysis method of organic semiconductor device SEMICONDUCTOR ENERGY LAB 2019-11-01 CN disclosed
CN-110115106-A Light-emitting component and the image-displaying member for using it DIC株式会社 2019-08-09 CN disclosed
CN-110003088-A Organic compound, light-emitting component, light emitting device, electronic equipment and lighting device 株式会社半导体能源研究所 2019-07-12 CN disclosed
CN-109075260-A Light-emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2018-12-21 CN disclosed
CN-105103327-B Light-emitting element, compound, organic compound, display module, lighting module, light-emitting device, display device, lighting device, and electronic device 株式会社半导体能源研究所 2018-09-07 CN disclosed