Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821223 | 0.79 | RAB9A (0.38) | ALDH1A1HTTNPSR1HTR1AHTR2A | |
| SCHEMBL572569 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HTTNPSR1HTR1AHTR2A | |
| SCHEMBL422638 | 0.76 | — | — | |
| SCHEMBL16415704 | 0.76 | — | — | |
| SCHEMBL3401349 | 0.74 | CYP1A2 (0.56) | ALDH1A1 | |
| SCHEMBL1363715 | 0.71 | — | — | |
| SCHEMBL788760 | 0.71 | — | — | |
| SCHEMBL302276 | 0.71 | — | — | |
| SCHEMBL189872 | 0.70 | CYP1A2 (0.59) | ALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL23963672 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341814-A | Jak kinase inhibitor and its application | 上海翔锦生物科技有限公司 | 2018-07-31 | — | — | CN | disclosed |