Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287774 | 0.82 | TBXAS1 (0.56) | TRPV1CASP2MAPTNAAAKMT2A | |
| SCHEMBL26398365 | 0.82 | GAA (0.43) | LMNAGAAMAPTKDM4EKMT2A | |
| SCHEMBL8535903 | 0.81 | TDP1 (0.40) | LMNAGAAMAPTKMT2ATBXAS1 | |
| SCHEMBL7297042 | 0.77 | TBXAS1 (0.51) | KMT2ATBXAS1 | |
| SCHEMBL8747369 | 0.77 | NAAA (0.54) | LMNAKDM4ENAAAHPGDEPHX1 | |
| SCHEMBL7742657 | 0.76 | GAA (0.42) | LMNAGAAMAPTKDM4EKMT2A | |
| SCHEMBL1075053 | 0.75 | GAA (0.46) | GAAMAPTKDM4EKMT2ATBXAS1 | |
| SCHEMBL30979824 | 0.75 | SELP (0.56) | TBXAS1 | |
| SCHEMBL5579468 | 0.75 | NAAA (0.51) | LMNAKDM4ENAAAHPGDEPHX1 | |
| SCHEMBL8278814 | 0.74 | TBXAS1 (0.48) | CASP2TBXAS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020179-B9 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2011-02-02 | — | — | EP | claimed |
| EP-1020179-B1 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2009-12-09 | — | — | EP | claimed |
| EP-1020179-B9 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2011-02-02 | — | — | EP | disclosed |
| EP-1020179-B1 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2009-12-09 | — | — | EP | disclosed |