Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL11669284 | 0.81 | RAB9A (0.48) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL1701348 | 0.79 | PIK3CD (0.51) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL27870814 | 0.79 | RAB9A (0.49) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL5712027 | 0.78 | MAPT (0.48) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL5758053 | 0.77 | LMNA (0.52) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL39888 | 0.77 | LMNA (0.52) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL178277 | 0.77 | MAPT (0.60) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL1714777 | 0.76 | AGXT (0.69) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL16003056 | 0.76 | MAPT (0.58) | RAB9ANPC1L3MBTL1GAAMAPT | |
| SCHEMBL9093746 | 0.76 | LMNA (0.71) | RAB9ANPC1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710327-B | It is beneficial to treat the compound of central nervous system disease and illness | 奥里梅德制药公司 | 2018-09-07 | — | — | CN | disclosed |