SCHEMBL1701348

SCHEMBL1701348

O=CCc1ccc(N2CCOCC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.51
PIK3CA P42336 1/20 0.51
PIK3CB P42338 1/20 0.51
PIK3CG P48736 1/20 0.51
PRKDC P78527 1/20 0.51
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 3/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
HTT P42858 2/20 0.50
GSK3B P49841 1/20 0.50
CYP1A2 P05177 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 1/20 0.49
KDM4E B2RXH2 2/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13680782 0.85 SLC13A5 (0.49) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL15551035 0.83 TRIM24 (0.61) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL1255409 0.83 SLC13A5 (0.47) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL13724480 0.83 AGXT (0.61) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL5758053 0.82 LMNA (0.52) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL6065386 0.82 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL29272968 0.81 SLC13A5 (0.46) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL14058774 0.81 HRH3 (0.67) ALDH1A1MAPTLMNARAB9ANPC1
SCHEMBL3304463 0.80 L3MBTL1 (0.54) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL25370544 0.80 LGMN (0.54) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109964175-B Photosensitive resin composition, color filter and image display device 东友精细化工有限公司 2023-06-20 CN disclosed
CN-109997079-B Self-luminous photosensitive resin composition, color filter and image display device manufactured by using same 东友精细化工有限公司 2023-03-10 CN disclosed
CN-105911820-B Self-luminous photosensitive resin composition, color filter and image display device 东友精细化工有限公司 2021-02-12 CN disclosed
US-10329409-B2 Photosensitive resin composition and display device including color conversion layer prepared by using the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-25 US disclosed
CN-104710385-B PDE10 inhibitor and compositions related and method 奥默罗斯公司 2018-11-09 CN disclosed
CN-107445919-A PDE10 inhibitor and compositions related and method 奥默罗斯公司 2017-12-08 CN disclosed
US-20170240728-A1 PHOTOSENSITIVE RESIN COMPOSITION AND DISPLAY DEVICE INCLUDING COLOR CONVERSION LAYER PREPARED BY USING THE SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2017-08-24 US disclosed
EP-2585459-A1 ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF Chiesi Farmaceutici S.p.A. (IT) 2013-05-01 EP disclosed
WO-2011161018-A1 ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHIESI FARMACEUTICI S.P.A. (IT) 2011-12-29 WO disclosed
WO-2010028193-A1 COMPOUNDS INCLUDING PIMELIC ACID DERIVATIVES AS HDAC INHIBITORS REPLIGEN CORPORATION (US) 2010-03-11 WO disclosed
EP-1748993-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2007-02-07 EP disclosed
WO-2005121134-A1 THIOPHENE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS F. HOFFMANN-LA ROCHE AG (CH) 2005-12-22 WO disclosed
WO-2005116000-A1 COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS IRM LLC (BM) 2005-12-08 WO disclosed
CN-1612042-A Colouring photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2005-05-04 CN disclosed
CN-1585775-A 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials ORTHO MCNEIL PHARM INC (US) 2005-02-23 CN disclosed
US-6825170-B2 ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-11-30 US disclosed
EP-1453847-A1 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS Ortho-Mcneil Pharmaceutical, Inc. (US) 2004-09-08 EP disclosed
WO-2003050132-A1 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2003-06-19 WO disclosed
EP-1196407-A1 N-IMIDAZOLYLMETHYL CARBOXAMIDES AS NITRIC OXIDE PRODUCTION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-04-17 EP disclosed
WO-2001002387-A1 N-IMIDAZOLYLMETHYL CARBOXAMIDES AS NITRIC OXIDE PRODUCTION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-01-11 WO disclosed