Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.80 |
| ▸ | CNR1 | P21554 | 2/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330099 | 0.89 | L3MBTL1 (1.00) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL14345990 | 0.84 | L3MBTL1 (0.80) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL18641957 | 0.82 | L3MBTL1 (0.76) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL6998874 | 0.79 | L3MBTL1 (0.71) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL14345980 | 0.78 | L3MBTL1 (0.70) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL3261601 | 0.76 | MAOB (0.78) | L3MBTL1MAOBSMN1; SMN2ALDH1A1ROCK2 | |
| SCHEMBL210149 | 0.75 | SMN1; SMN2 (0.67) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL19380255 | 0.75 | L3MBTL1 (0.66) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 | |
| SCHEMBL28863161 | 0.75 | HDAC1 (0.60) | HDAC3HDAC1HDAC2RAB9ANAMPT | |
| SCHEMBL17903693 | 0.74 | L3MBTL1 (0.70) | L3MBTL1CNR1CNR2MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685516-A | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-108431007-B | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108431007-A | PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER | 洛克索肿瘤学股份有限公司 | 2018-08-21 | — | — | CN | disclosed |