Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457535 | 0.84 | ROCK2 (1.00) | MAOBROCK2ROCK1 | |
| SCHEMBL5330099 | 0.83 | L3MBTL1 (1.00) | MAOBROCK2L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL5328632 | 0.82 | MAOB (0.79) | MAOBL3MBTL1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL18763169 | 0.79 | RAB9A (0.60) | MAOBROCK2ROCK1SMN1; SMN2RAB9A | |
| SCHEMBL28147012 | 0.77 | RAB9A (0.71) | SMN1; SMN2RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL13457054 | 0.77 | ROCK2 (0.64) | MAOBROCK2ROCK1MMP13 | |
| SCHEMBL3264656 | 0.77 | ROCK2 (0.68) | MAOBROCK2ROCK1 | |
| SCHEMBL14346517 | 0.76 | MAOB (0.72) | MAOBROCK2RAB9AKMT2AMEN1 | |
| SCHEMBL19828200 | 0.76 | SENP1 (0.61) | SMN1; SMN2RAB9AGAAMAPTNPC1 | |
| SCHEMBL14345990 | 0.76 | L3MBTL1 (0.80) | MAOBROCK2L3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |