Trolamine

Trolamine

SCHEMBL28239093

CC(O)N(C)C.OCCN(CCO)CCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylaminoethanol SCHEMBL8154143 0.87 CYP1A2 (0.42) MAPTCHRNB2CHRNB4CHRNA3CHRNA4
Trolamine SCHEMBL27756311 0.85 MAPT (0.42) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL8515537 0.85 MAPT (0.42) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL6455111 0.85 MAPT (0.42) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL6682064 0.85 MAPT (0.42) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL11034532 0.85 MAPT (0.32) MAPT
Trolamine SCHEMBL740171 0.82 MAPT (0.40) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL27728576 0.82 MAPT (0.40) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL11507708 0.82 MAPT (0.40) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL27571328 0.82 MAPT (0.40) MAPTTDP1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495700-A Supporting layer for forward osmosis membrane OASYS水有限公司 2018-09-04 CN disclosed