Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514914 | 0.83 | HTR2A (0.40) | PLAUDRD2DRD3HTR6ITGB3 | |
| SCHEMBL1206291 | 0.83 | HTR2A (0.40) | PLAUDRD2DRD3HTR6ITGB3 | |
| Hydrochloric Acid SCHEMBL3710885 | 0.82 | HTR2A (0.39) | PLAUDRD2DRD3HTR6ITGB3 | |
| SCHEMBL21335649 | 0.80 | DRD2 (0.47) | PLAUDRD2DRD3HTR6 | |
| Bromide SCHEMBL9757324 | 0.75 | CAPN1 (0.44) | ALDH1A1PLAUDRD2DRD3HTR6 | |
| SCHEMBL8179926 | 0.75 | DRD2 (0.42) | DRD2DRD3HTR6 | |
| SCHEMBL28959626 | 0.75 | PLAU (0.38) | GAAPLAUDRD2DRD3HTR6 | |
| SCHEMBL8853672 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL7998432 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL9326541 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1GAAMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430515-A | Include the antibody conjugates of TOLL- sample receptor stimulating agents | 诺华股份有限公司 | 2018-08-21 | — | — | CN | disclosed |