Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2823915

O=C(O)C(F)(F)F.O=C(O)CCc1ccc(OCc2ccc(CN3CCC(c4cnccn4)C3)cc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.51
LTA4H P09960 1/20 0.47
EPHX2 P34913 1/20 0.47
SLC6A5 Q9Y345 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HRH4 Q9H3N8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13887159 0.95 FFAR1 (0.54) FFAR1LTA4HEPHX2FFAR4TP53
SCHEMBL4460376 0.89 LTA4H (0.44) FFAR1LTA4HEPHX2SLC6A5TP53
Trifluoroacetic Acid SCHEMBL2827609 0.83 LTA4H (0.56) FFAR1LTA4HEPHX2SLC6A5FFAR4
Trifluoroacetic Acid SCHEMBL2823887 0.78 LTA4H (0.69) FFAR1LTA4HEPHX2SLC6A5FFAR4
SCHEMBL13065796 0.78 LTA4H (0.61) FFAR1LTA4HEPHX2FFAR4TP53
Trifluoroacetic Acid SCHEMBL2824006 0.76 LTA4H (0.52) FFAR1LTA4HEPHX2SLC6A5FFAR4
SCHEMBL2826986 0.75 HRH3 (0.61) FFAR1LTA4HEPHX2FFAR4TP53
Trifluoroacetic Acid SCHEMBL2827623 0.75 LTA4H (0.57) FFAR1LTA4HEPHX2FFAR4TP53
SCHEMBL2827832 0.74 FFAR1 (0.60) FFAR1FFAR4HRH3
SCHEMBL2830782 0.74 FFAR1 (0.60) FFAR1SLC6A5FFAR4TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731505-B1 ALKOXYPHENYLPROPANOIC ACID DERIVATIVES TAKEDA PHARMACEUTICAL (JP) 2015-01-14 EP disclosed
EP-2253315-A1 Alkoxyphenylpropanoic acid derivatives Takeda Pharmaceutical Company Limited (JP) 2010-11-24 EP disclosed
US-7517910-B2 Alkoxyphenylpropanoic acid derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-04-14 US disclosed
US-20070213364-A1 Alkoxyphenylpropanoic Acid Derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-09-13 US disclosed
EP-1731505-A1 ALKOXYPHENYLPROPANOIC ACID DERIVATIVES Takeda Pharmaceutical Company Limited (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213364-A1 Alkoxyphenylpropanoic Acid Derivatives GPR119, FFAR1, GPR55 FFAR1 2/4885LTA4H 476/4885EPHX2 2261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.