Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394619 | 0.84 | APP (0.63) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8687683 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28238269 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8685326 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28477449 | 0.84 | HTR6 (0.55) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8685723 | 0.81 | SLC2A1 (0.55) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8687577 | 0.81 | APP (0.53) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8685511 | 0.81 | ADCYAP1R1 (0.55) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8686330 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL8685733 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | claimed |
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | disclosed |