Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640170 | 0.90 | ALDH1A1 (0.78) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8851674 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL12672463 | 0.88 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL12672462 | 0.88 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL27712513 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL51729 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL301798 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL366844 | 0.83 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL27864178 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27896729 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430967-A | The preparation of the matrix treatments composition of antimicrobial containing sulfanilamide (SN) and the antimicrobial containing sulfanilamide (SN) | 纳米安全涂层公司（佛罗里达公司3 P 14000024914) | 2018-08-21 | — | — | CN | disclosed |