Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Anthranilate SCHEMBL30130467 | 0.85 | HSD17B10 (0.68) | RAB9AKDM4ESMN1; SMN2NPC1CASP3 | |
| Ethyl Anthranilate SCHEMBL468375 | 0.85 | HSD17B10 (0.68) | RAB9AKDM4ESMN1; SMN2NPC1CASP3 | |
| SCHEMBL1460556 | 0.85 | TSHR (0.67) | KDM4ESMN1; SMN2GAATSHRALDH1A1 | |
| Phthalic Acid SCHEMBL27284496 | 0.85 | TSHR (0.66) | RAB9ASMN1; SMN2NPC1GAATSHR | |
| SCHEMBL184136 | 0.84 | ALDH1A1 (0.62) | RAB9AKDM4EAGTR1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6383958 | 0.83 | TSHR (0.65) | KDM4EGAATSHRALDH1A1KMT2A | |
| Ethyl Benzoate SCHEMBL31443235 | 0.80 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2NPC1GAATSHR | |
| SCHEMBL10935587 | 0.80 | FABP4 (0.61) | RAB9AKDM4EAGTR1NPC1FABP4 | |
| Ethyl Benzoate SCHEMBL25388294 | 0.79 | LMNA (0.70) | RAB9ASMN1; SMN2NPC1GAATSHR | |
| Ethyl Benzoate SCHEMBL2762273 | 0.79 | LMNA (0.70) | RAB9ASMN1; SMN2NPC1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358841-A | A kind of 4- ((2- substd quinolines -4- bases) amino) benzoyl hydrazine analog derivative and the preparation method and application thereof | 厦门大学 | 2018-08-03 | — | — | CN | disclosed |