Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617230 | 0.83 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL7911621 | 0.83 | LMNA (0.43) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL3211927 | 0.81 | MAPT (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL27617206 | 0.76 | MAPT (0.36) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL29145843 | 0.76 | SLC6A2 (0.47) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8079401 | 0.76 | PTGER1 (0.49) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL1003999 | 0.74 | L3MBTL1 (0.38) | MAPTMAPK1TDP1L3MBTL1KDM1A | |
| SCHEMBL10517942 | 0.73 | KDM1A (0.49) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL15129422 | 0.73 | KDM1A (0.60) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL30080427 | 0.73 | MAPT (0.58) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936955-B | Thiadiazoles analog and treatment lack the method for relevant illness with SMN | 诺华股份有限公司 | 2018-08-28 | — | — | CN | disclosed |